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EU funding (€8,000,000): Collaboration for Prevention and Treatment of MDR Bacterial Infections Hor1 Nov 2019 EU Research and Innovation programme "Horizon"
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Collaboration for Prevention and Treatment of MDR Bacterial Infections
The loss of antibiotic effectiveness due to increasing antimicrobial resistance (AMR) is a serious threat to global public health. The IMI2 AMR Accelerator will develop new agents to treat and prevent infections caused by MDR and XDR bacteria, including Mycobacterium tuberculosis and non-tuberculous mycobacteria. The COMBINE proposal addresses Pillar A, the Capability Building Network (CBN) of the AMR Accelerator programme. The COMBINE consortium will form a Coordination and Support Office (CSO) that will support the delivery of projects across the AMR Accelerator, as well as with efficient communication among projects of the Accelerator and within the AMR community. In addition, we will establish an IT infrastructure that will allow for the FAIRification, collection, aggregation, storage, sharing, and analysis of vaccine and antibacterial preclinical and clinical data sets. When setting up the CSO, we will build on learnings from the two IMI ND4BB projects: ENABLE (an antibacterial discovery and development engine) and TRANSLOCATION (which has built an information centre for data sharing). COMBINE partners will work to accelerate scientific discoveries in the AMR field by optimisation and standardisation of animal infection models, and development of improved models for translation of preclinical animal efficacy data and statistical analysis of clinical data. This will set new standards for the translational and predictive relevance of preclinical data and facilitate optimized design for new clinical trials. Results will feed into study and trial design throughout the AMR Accelerator to achieve more stringent and reliable development programmes.
Funded Companies:
| Company name | Funding amount |
| €338,228 | |
| BIOCOM INTERRELATIONS GmbH | €356,289 |
| BIOCOM MEDIA AG | €293,711 |
| BUNDESINSTITUT für IMPFSTOFFE UND BIOMEDIZINISCHE ARZNEIMITTEL | €1,466,860 |
| Beam Alliance | €104,255 |
| EVOTEC INTERNATIONAL GmbH | €0.00 |
| FRAUNHOFER GESELLSCHAFT ZUR FORDERUNG DER ANGEWANDTEN FORSCHUNG e. V. | €800,000 |
| €0.00 | |
| €800,625 | |
| Janssen Pharmaceutica N.V. | €0.00 |
| Statens Serum Institut | €812,500 |
| Uppsala Universitet | €3,027,532 |
Source: https://cordis.europa.eu/project/id/853967
The filing refers to a past date, and does not necessarily reflect the current state.
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