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EU funding (€3,000,000): Infradev - European Paediatric Translational Research Infrastructure Hor1 Jan 2018 EU Research and Innovation programme "Horizon"
Overview
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Infradev - European Paediatric Translational Research Infrastructure
The general objective of this project is to design the framework for the European Paediatric Translational Research Infrastructure (EPTRI), a new Research Infrastructure (RI) aimed to enhance technology-driven paediatric research in discovery and early development phases to be translated into clinical research and paediatric use of medicines. The starting point of the proposal is the serious lack of medicines for children in EU and worldwide as well as the lack of a developmental model for paediatric medicines that integrates technology-driven aspects with the methodological, ethical and regulatory framework. The design for this new RI will be based on the following main pillars: • to harness efficiency and delivery of paediatric research activities and services strengthening collaboration within the scientific paediatric community; • to be a complementary RI in the context of the existing RIs covering the current gaps, while avoiding any duplication; • to develop a one-stop-shop for advice in paediatric drug development. To prepare a valuable Conceptual Design Report (CDR), the project encompasses three phases. During the Context Analysis phase, that will be performed in 5 technical and scientific domains (1- Paediatric Medicines Discovery, 2- Paediatric Biomarkers and Biosamples, 3-Developmental Pharmacology, 4-Paediatric Medicines Formulations and Medical Devices, 5- Underpinning Medicines Development to Paediatric Clinical Studies) the perceived value and the possible gaps to be covered will be estimated by enquiring the scientific communities and many other Stakeholders. During the Operational phase, the different components of the new RI will be depicted including governance model strategies for interaction with national Authorities and the existing RIs, the IT-architecture model, services to be provided and a business plan. Finally, a Feasibility phase is proposed to develop virtual exercises simulating the operations of the RI. The final result of the project will be the CDR to realize EPTRI.
Funded Companies:
| Company name | Funding amount |
| Assistance Publique Hopitaux de Paris | €147,500 |
| €141,875 | |
| Biobanks AND Biomolecular Resources Research Infrastructure Consortium (Bbmri-Eric) | €130,000 |
| Consorzio Per Valutazioni Biologiche E Farmacologiche | €795,650 |
| €100,000 | |
| Ecrin European Clinical Research Infrastructure Network | €55,000 |
| €175,625 | |
| Fondazione Per LA Ricerca Farmacologica Gianni Benzi Onlus | €0.00 |
| Fundacio Privada Per A La Recerca i La Docencia Sant Joan de DEU | €178,125 |
| €35,000 | |
| €72,875 | |
| Instytut Pomnik Centrum Zdrowia Dziecka | €97,500 |
| €123,100 | |
| €10,000.00 | |
| €0.00 | |
| Ospedale Pediatrico Bambino Gesu | €100,625 |
| €32,375 | |
| SWISS CLINICAL TRIAL ORGANISATION (SCTO) | €13,750.00 |
| €65,250 | |
| €21,375 | |
| €125,000 | |
| TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY | €76,250 |
| Tartu Ulikool | €13,750.00 |
| €0.00 | |
| The University of Liverpool | €108,750 |
| €103,750 | |
| Universita' Degli Studi DI Milano-Bicocca | €0.00 |
| Universitair Medisch Centrum Utrecht | €53,125 |
| Universitair Ziekenhuis Antwerpen | €10,000.00 |
| Universiteit Antwerpen | €5,000.00 |
| €173,750 | |
| Västra Götalandsregionen | €35,000 |
Source: https://cordis.europa.eu/project/id/777554
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